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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HRH1
All Species:
18.48
Human Site:
T361
Identified Species:
31.28
UniProt:
P35367
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35367
NP_000852.1
487
55784
T361
D
S
Q
S
F
S
R
T
D
S
D
T
T
T
E
Chimpanzee
Pan troglodytes
Q9N2B2
487
55605
T361
D
S
Q
S
F
S
R
T
D
S
D
T
T
T
E
Rhesus Macaque
Macaca mulatta
P56490
532
60122
V385
A
Y
K
F
R
L
V
V
K
A
D
G
T
Q
E
Dog
Lupus familis
XP_541769
536
61594
T410
D
S
Q
S
F
S
R
T
D
S
D
T
P
T
E
Cat
Felis silvestris
Mouse
Mus musculus
P70174
488
55663
T362
R
Q
S
F
S
R
T
T
D
S
D
T
S
I
E
Rat
Rattus norvegicus
P31390
486
55674
T360
Q
Q
S
F
S
R
T
T
D
S
D
T
S
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505379
489
54959
S363
L
T
S
C
Q
T
D
S
E
S
P
V
E
P
A
Chicken
Gallus gallus
P30372
466
51547
T352
T
T
V
E
I
V
G
T
N
G
D
E
K
Q
N
Frog
Xenopus laevis
P30544
484
54107
E369
E
C
A
I
P
L
P
E
Q
A
N
N
R
P
V
Zebra Danio
Brachydanio rerio
NP_001036196
534
61056
V408
D
I
H
N
Y
T
A
V
L
C
T
P
P
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IS44
506
56459
A401
K
D
K
K
N
S
Q
A
S
R
F
T
I
Y
K
Honey Bee
Apis mellifera
XP_395477
546
60788
S417
K
Q
S
Q
P
I
M
S
N
A
S
S
Q
T
H
Nematode Worm
Caenorhab. elegans
Q18775
517
58629
Q375
M
S
L
S
S
N
S
Q
M
V
M
T
S
P
L
Sea Urchin
Strong. purpuratus
NP_001012721
677
76342
T523
S
P
T
H
L
L
P
T
D
N
I
S
P
D
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
27
78.5
N.A.
78
78.8
N.A.
60.1
27.3
27.7
41.3
N.A.
28.6
28.3
26.8
29.2
Protein Similarity:
100
99.1
44.7
83.4
N.A.
84.6
85.6
N.A.
70.7
47.2
44.5
57.1
N.A.
48.8
43
46.8
49
P-Site Identity:
100
100
20
93.3
N.A.
40
40
N.A.
6.6
13.3
0
6.6
N.A.
13.3
6.6
20
13.3
P-Site Similarity:
100
100
33.3
93.3
N.A.
46.6
46.6
N.A.
33.3
26.6
20
33.3
N.A.
33.3
33.3
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
8
8
0
22
0
0
0
0
8
% A
% Cys:
0
8
0
8
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
29
8
0
0
0
0
8
0
43
0
50
0
0
8
0
% D
% Glu:
8
0
0
8
0
0
0
8
8
0
0
8
8
0
43
% E
% Phe:
0
0
0
22
22
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
0
8
0
8
0
0
0
% G
% His:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
8
0
8
8
8
0
0
0
0
8
0
8
15
0
% I
% Lys:
15
0
15
8
0
0
0
0
8
0
0
0
8
0
8
% K
% Leu:
8
0
8
0
8
22
0
0
8
0
0
0
0
0
8
% L
% Met:
8
0
0
0
0
0
8
0
8
0
8
0
0
0
0
% M
% Asn:
0
0
0
8
8
8
0
0
15
8
8
8
0
0
15
% N
% Pro:
0
8
0
0
15
0
15
0
0
0
8
8
22
22
8
% P
% Gln:
8
22
22
8
8
0
8
8
8
0
0
0
8
15
0
% Q
% Arg:
8
0
0
0
8
15
22
0
0
8
0
0
8
0
0
% R
% Ser:
8
29
29
29
22
29
8
15
8
43
8
15
22
8
0
% S
% Thr:
8
15
8
0
0
15
15
50
0
0
8
50
22
29
0
% T
% Val:
0
0
8
0
0
8
8
15
0
8
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
8
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _